Since Dr. Matthew Johnson first appeared on 12 Geniuses in September of 2020 to discuss The Future of Psychedelics, popular opinion in favor of this category of drugs has surged and so has the research and potential uses for psilocybin, MDMA, LSD, ayahuasca, and other drugs that fit into the broader category of psychedelics. Dr. Johnson and his research have been critical to fueling these growing trends. In this interview, Dr. Johnson discusses the advancements in psychedelic research that have been made in the last few years, how favorable public opinion about the use of these once taboo drugs continues to grow, and he closes the conversation with his sobering advice for people who are experimenting on their own with these drugs, going on weekend psychedelic retreats, or even going to South America to have ayahuasca experiences with a shaman. Dr. Matthew Johnson is Senior Investigator in Psychedelics at Sheppard Pratt and Professor of Psychiatry and Behavioral Sciences at Johns Hopkins University where he is one of the world’s most published scientists on the human effects of psychedelics. He had conducted seminal research in the behavioral economics of drug use, addiction, and risk behavior. Dr. Johnson published psychedelic safety guidelines in 2008, helping to resurrect psychedelic research.