Dr Ross Chapman studies the molecular events triggered by DNA damage detection, and why defects in these events lead to immune deficiency and cancer in humans. GENOME INTEGRITY
Whilst controlled DNA breaks allow for our vast repertoire of antibodies, DNA damage happening out of context can lead...
Published 04/28/16
Misfolded proteins can either create the loss of a cellular function, or escape degradation, causing aggregation diseases. Dr John Christianson's research focusses on ER-associated degradation, which is responsible for clearing non-functional and orphan translation products. These processes play...
Published 02/04/16