Episodes
Published 03/24/24
Moderator: Francesco Di Lorenco (Rome, Italy) Guest: Dag Aarsland (London, United Kingdom) Francesco Di Lorenco and Prof. Dag Aarsland discuss managing behavioral symptoms in dementia, highlighting the burden on patients and families. They stress the importance of timely treatment and challenges in diagnosis. They mention brexpiprazole's FDA approval for Alzheimer's agitation and the need for careful monitoring. Early detection of psychiatric symptoms in neurological diseases is crucial,...
Published 03/24/24
Moderator: Massimo Filippi (Milan, Italy) Guest: Federica Agosta (Milan, Italy) In this week’s episode Prof. Massimo Filippi and Prof. Federica Agosta discuss frontotemporal dementia (FTD) emphasizing the role of neuroimaging (MRI and FDG PET) in early diagnosis. They highlight MRI for identifying crucial patterns and FDG PET for detecting metabolic changes. Early detection is crucial for future treatments. Connectomics, studying brain networks, aids in predicting FTD progression. Emerging...
Published 03/17/24
Moderator: Youssuf Saleh (Oxford, United Kingdom) Guest: Sebastiaan Engelborghs (Brussel, Belgium) Youssuf Saleh interviews Prof. Sebastiaan Engelborghs on Alzheimer's biomarkers, focusing on amyloid and tau. They discuss diagnostic challenges, the need for prognostic markers, and potential serum markers like neurofilament light. Engelborghs highlights Alzheimer's complexity and the role of omics studies in patient subpopulations. The interview concludes with optimism for blood-based...
Published 03/10/24
Moderator: Svetlana Tomic (Osijek, Croatia) Guest: Veronica Cabreira (Edinburgh, United Kingdom) In this episode of eanCast, Prof. Svetlana Tomic and Dr. Veronica Cabreira delve into the definition functional cognitive impairment. This disorder, affecting a significant number of patients at memory clinics, is marked by severe attention and concentration issues, and excessive self-monitoring of cognitive performance. Diagnosis hinges on cognitive symptoms, distress, and internal inconsistency....
Published 03/03/24
Moderator: Federica Montagnese (Munich, Germany) Guest: John Vissing (Copenhagen, Denmark) In this week's episode, Federica Montagnese hosts Professor John Vissing as they delve into the intricate world of diagnosing muscular dystrophies. The discussion revolves around the crucial role of neuromuscular examinations and the significance of medical history, including school performance. Specific signs like myotonia and facial signs are explored, alongside the evolving landscape of genetic...
Published 02/25/24
Moderator: Gabriele Siciliano (Pisa, Italy) Guest: Antonio Toscano (Messina, Italy) Prof. Antonio Toscano is hosted by Prof. Gabriele Siciliano as he emphasizes the enduring significance of muscle biopsy in diagnosing neuromuscular disorders, particularly in cases of progressive muscle weakness. The episode stresses the need for a comprehensive diagnostic strategy, combining genetic testing with muscle biopsy, guided by clinical and imaging assessments. Overall, the episode underscores the...
Published 02/18/24
Moderator: Gabriele Siciliano (Pisa, Italy) Guest: Tiziana Mongini (Torino, Italy) In this episode, Prof. Gabriele Siciliano and Prof. Tiziana Mongini discuss a recent paper on Bag3 gene mutations linked to neurogenic distal muscle atrophy. They explore the evolving understanding of muscle dystrophies, the importance of genetic and molecular aspects, and challenges in diagnosis. Mongini underscores the significance of ancillary exams like neurophysiology and muscle MRI. They emphasize the...
Published 02/13/24
Moderator: Federica Montagnese (Munich, Germany) Guest: Magda Mroczek (Basel, Switzerland) In this podcast, Dr. Federica Montagnese interviews Dr. Magdalena Mroczek about gene mutations and variants in neuromuscular disorders, with a focus on muscular dystrophies. They discuss the impact of advanced technologies on genetic testing, highlighting the importance of clinical data and collaboration between clinicians and geneticists. The conversation touches on challenges in interpreting variants,...
Published 02/04/24
Moderator: Barbara Tettenborn (St.Gallen, Switzerland) Guest: Matthias Endres (Berlin, Germany) In this episode, Barbara Tettenborn interviews Professor Matthias Endres, professor and chair of Neurology at the Charité Hospital in Berlin. The conversation delves into the connection between stroke and cardiology. Endres introduces the concept of stroke-induced atrial fibrillation, distinguishing it from pre-existing AF. They discuss the stroke heart syndrome, underlining the increased risk of...
Published 01/28/24
Moderator: Benedetta Storti (Milan, Italy) Guest: Anita Arsovska (Skopje, North Macedonia) Benedetta Storti hosts Prof. Arsovska as they explore rare causes of strokes, covering conditions like cardiomyopathy, fibromuscular dysplasia, and immune-related factors. Arsovska stresses the significance of a comprehensive diagnostic approach, discussing specific features in tests and advocating for thorough investigations. The podcast addresses potential errors in diagnostic pathways and...
Published 01/21/24
Moderator: Barbara Tettenborn (St. Gallen, Switzerland) Guest: Thomas Meinel (Bern, Switzerland) Thomas Meinel, a clinician scientist at the Burn Stroke Research Center in Switzerland, is hosted by Barbara Tettenborn as they discuss covert cerebrovascular disease. His research, particularly on strokes in patients on anticoagulation, is explored, highlighting the frequency and clinical implications of covert cerebrovascular lesions. Meinel emphasizes the current lack of clear evidence for...
Published 01/14/24
Moderator: Rolf Fronczek (Leiden, The Netherlands) Guest: Matilde Leonardi (Milan, Italy) Celebrate the end of the year with us with this special episode on Brain Health! Rolf Fronczek hosts Matilde Leonardi discussing her international neurology career and passion for Brain Health. She highlights the WHO Global Action Plan on epilepsy, stresses the increasing global burden of neurological diseases, and advocates for preventative measures. Leonardi details EAN's Brain Health Strategy, urging...
Published 01/07/24
Moderator: Barbara Tettenborn (St. Gallen, Switzerland) Guest: Didier Leys (Lille, France) In this eanCast episode, Barbara Tettenborn interviews Didier Leys, Editor-in-Chief of the European Journal of Neurology, marking its 30th anniversary. Leys discusses the journal's evolution, challenges, and current impact factor of five. He outlines his daily editorial duties, stressing manuscript selection, ethical standards, and team management. Future plans include webinars, a history special...
Published 12/31/23
Moderator: Johann Sellner (Mistelbach, Austria) Guest: Tamuna Akhvlediani (Tbilisi, Georgia) In this podcast episode, Prof. Johann Sellner interviews Prof. Tamuna Akhvlediani about the neurological aspects of new antiviral drugs for SARS-CoV-2. They discuss drugs like monoclonal antibodies, paxlovid, and remdesivir, emphasizing their mechanisms and potential applications beyond COVID-19. Prof. Akhvlediani details neurological side effects observed in trials and significant drug...
Published 12/24/23
Moderator: Johann Sellner (Mistelbach, Austria) Guest: Tamuna Akhvlediani (Tbilisi, Georgia) In this last episode on Infectious Diseases, Prof. Johann Sellner and Prof. Tamuna Akhvlediani explore nosocomial infections of the central nervous system (CNS). They cover the definition, common pathogens, and prevention methods like infection control and standardized surgery. Prof. Akhvlediani specifies prevalent CNS infections and addresses challenges in prevention and treatment, notably due to...
Published 12/17/23
Moderator: Tamuna Akhvlediani (Tbilisi, Georgia) Guest: Johann Sellner (Mistelbach, Austria) In this week’s podcast hosted by Dr. Tamuna Akhvlediani, Prof. Johann Sellner discusses the connection between Epstein-Barr virus (EBV) and multiple sclerosis (MS). They explore the immune-mediated nature of MS, focusing on the impact of EBV and recent studies linking its infection to MS development. The episode delves into the controversies, hypotheses, and potential therapies related to EBV and...
Published 12/10/23
Moderator: Tamuna Akhvlediani (Tbilisi, Georgia) Guest: Johann Sellner (Mistelbach, Austria) Dr. Tamuna Akhvlediani hosts Professor Johann Sellner in a podcast discussing the impact of COVID-19 on neuro infections. Professor Sellner covers global neuro infections, the decline during lockdowns, and the effectiveness of measures like face masks and vaccination. The episode emphasizes lessons learned, including insights into chronic neuro infection care disruptions and challenges, such as...
Published 12/03/23
Moderator: Yildiz Değirmenci (Istanbul, Turkey) Guest: Antonio Farina (Florence, Italy) This week, Dr. Yildiz Değirmenci and Dr. Antonio Farina discuss life-threatening neurological toxicities from immune checkpoint inhibitors. Dr. Farina highlights high fatality rates, long-term disabilities, and the urgency of early recognition and treatment. The episode explores management, including discontinuation and corticosteroids, and factors influencing outcomes. It touches on the association...
Published 11/26/23
Moderator: Antonio Malvaso Guest: Stefania Cuzzubbo Dr. Antonio Malva hosts Dr. Stefania Cuzzubbo to discuss neurological complications from cancer immunotherapy. Dr. Cuzzubbo highlights immune-related adverse events, focusing on peripheral nervous system issues. The importance of early diagnosis using MRI, lumbar puncture, and nerve studies is emphasized. Treatment involves promptly stopping the drug and using steroids, with alternative therapies explored for steroid-refractory cases....
Published 11/19/23
Moderator: Antonio Malvaso (Pavia, Italy) Guest: Alberto Vogrig (Udine, Italy) In this episode of EAN Cast Weekly Neurology, Dr. Antonio Malvaso, a neurology resident, welcomes Dr. Alberto Vogrig, an international expert in the field of paraneoplastic neurological syndromes. They discuss the definition of these syndromes, emphasizing the causal relationship with cancer and their immune-mediated pathogenesis. They also talk about the revised diagnostic criteria and the importance of clinical...
Published 11/12/23
Moderator: Alberto Vogrig (Udine, Italy) Guest: Giulia Berzero (Milan, Italy) In this episode Dr. Alberto Vogrig is joined by Dr. Giulia Berzero to discuss the clinical approach to neurological symptoms in patients with cancer. She highlights the increasing occurrence of neurological complications in cancer patients due to improved survival rates and novel cancer treatments. Dr. Berzero emphasizes the importance of considering patient-related factors, tumor-related factors, and treatment...
Published 11/05/23
Moderator: Panagiotis Zis (Nicosia, Cyprus) Guest: Peter Van den Bergh (Brussels, Belgium) In this episode of the EAN Cast, Prof. Zis is joined by Prof. Van den Bergh to discuss the recently updated guidelines for diagnosing and treating Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP). The existing guidelines were last revised over a decade ago, and this new version aims to reflect the latest advancements in clinical and basic research. Prof. Van den Bergh highlights the...
Published 10/22/23
Moderator: Thomas Berger (Vienna, Austria) Guest: Wolfgang Grisold (Vienna, Austria) In this podcast episode of EAN Cast, Professor Thomas Berger, Chair of the Department of Neurology at the Medical University in Vienna, and Professor Wolfgang Grisold, the current president of the World Federation of Neurology, discuss two important topics. First, they delve into the history and implementation of the World Health Organization's (WHO) Intersectoral Global Action Plan for epilepsy and other...
Published 10/15/23
Moderator: Yıldız Değirmenci (Istanbul, Turkey) Guest: Panagiotis Zis (Nicosia, Cyprus) In this podcast episode Dr. Yıldız Değirmenci is joined by Dr. Panagiotis Zis to discuss peripheral neuropathies. Dr. Panagiotis Zis explains that peripheral neuropathy refers to diseases or disorders of the peripheral nerves, including mono neuropathies affecting single nerves and poly neuropathies affecting multiple nerves. The clinical symptoms of peripheral neuropathy vary depending on the type and...
Published 10/08/23