Inside Matters Dr James McIlroy
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- Health & Fitness
Conversations with the brightest, most forward-thinking minds in health, fitness, science, nutrition and business. In-depth discussions about how our gut microbiome impacts our health, well-being, mood and much more.
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Episode 033 - Dr Saman Maleki - Is the future of oncology found in the microbiome?
The following is a conversation with Dr Saman Maleki, associate professor at Western University with a special focus on oncology, immuno oncology, microbiology, and everything to do with the immune system and the microbiome.
Dr Maleki is a pioneer and a world leader in the field of sensitising tumours to immunotherapy through modulating the microbiome.
During this conversation, we talked about the state of the art associated with the microbiome and cancer. So if you're interested in how cancer impacts the microbiome and how the microbiome impacts cancer you should listen to this episode. We delved into what the latest evidence is for the use of FMT in making a particular type of cancer therapy called immunotherapy better for treating particular cancers.
We talked about the journey from doing the first trials to the area where they are now, which is raising funds to do much larger trials that should definitively prove that changing the microbiome can massively improve response rates to cancer therapies.
Even as someone who's got their finger on the pulse of this field, I left the conversation enthusiastic and excited about the potential in the future for developing efficient microbiome treatments to tackle cancer.
00:00:00 Introduction
00:01:38 First interest in the microbiome
00:05:46 FMT for C-Diff patients
00:09:11 Using the immune system to treat cancer
00:19:03 Microbiome research for oncology
00:23:46 Journey from first study
00:27:30 Stimulating immune system with FMT
00:39:09 Chemotherapy, pancreatic cancer and the microbiome
00:48:29 Novel cell therapy and chemotherapy
00:49:02 Future of immunotherapy
00:52:32 Immune therapy response in cancer treatment
00:55:41 Antibiotics and cancer treatment -
Episode 032 - Sonny Drinkwater -co-founder of WellEasy
The following is a conversation with Sonny Drinkwater, an entrepreneur and co-founder of WellEasy, which is a membership-based online platform that aims to make healthy living accessible and affordable for everybody.
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Biome Bites Ep012 - Plans for the Podcast in 2024
In this Biome Bite, Dr James McIlroy chats about the progress of the Inside Matters Podcast.
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Episode 031 - Diets, Fibre, Supplements and the Microbiome With Dr Petra Louis
The following is a conversation with Dr. Petra Louis, Senior Research Fellow at the Rowett Institute for Nutrition and Health at the University of Aberdeen.
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Episode 030 - Erin Kenney - A Dietician's Approach to Gut Health
The following is a conversation with Erin Kenny, the CEO of Nutrition Rewired. Erin is a registered dietitian with a Master’s in nutritional science.
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Episode 029 - Mollie Hughes - the mindset to achieve great things
The following is a conversation with Mollie Hughes, a British alpinist, world record holder, company director, and entrepreneur.
This podcast will appeal to anybody and everybody. It's very easy to listen to Mollie speak and you can kind of get a sense of what it takes to summit Everest and go to the South Pole. She broke the world record for becoming the youngest woman to climb both sides of Mount Everest and the youngest woman to ski solo to the South Pole. And now she's building an amazing adventure business, going around the world talking about her endeavours, and writing a book.
We explore how Mollie developed her mindset both before and during her incredible quests, she explains what it’s like to be caught in an 8-day whiteout on the South Pole and how affirmations helped keep her skis moving.
Everyone can get something practical from this conversation, especially when it comes to developing a mindset to enable you to achieve your goals and deal with adversity along the way.
Timestamps:
00:00:00 Introduction
00:01:33 Mollie’s background
00:05:00 Tackling extreme activities
00:08:59 Controlling fear
00:10:46 Deciding to climb Everest
00:11:34 Fitness to climb Everest
00:15:00 Costs to climb Everest
00:17:47 Kit required to climb Everest
00:20:14 Mollie’s first climb of Everest
00:23:29 Everest’s death zone
00:26:22 Hillary’s Step
00:32:51 Communication and food on Everest
00:35:06 Climbing north face of Everest
00:44:59 Human landmarks on Everest
00:52:31 Skiing to the South Pole
00:58:58 Dealing with isolation
01:07:16 Silence of the South Pole
01:09:20 Joining Ocean Vertical