Can adversity ever  be an advantage? Can early trauma shape future success? Times’ columnists, Rachel Sylvester and Alice Thomson interview notable people about the challenges they faced in their lives. What impact did these have on their identities and on their careers. In his fifties, the Nobel Prize winning geneticist Sir Paul Nurse made a shocking discovery that revealed that his childhood was based on secrets and lies. No-one in his family was who he thought they were. Paul discusses his remarkable scientific achievements, his educational triumphs and the importance of failure, and  how the unravelling of his own genetic certainties  affected his life, his work and his views on nature versus nurture.   See acast.com/privacy for privacy and opt-out information.