Comedian/writer/actress Laura Kightlinger (@KingKightlinger) joins Matt, Jesse and Andy to talk about spontaneous human combustion, Bourbon Room comedy shows in Hollywood, the story behind Andy's various bands,  the Uranus story we don't want to cover, how one atom can change a parrot's color, blurb machine Peter Travers, peacock spiders, a blue whale that's been leaking oil for 26 years and a flu strain that we've basically beaten. 

Screenwriter James Lamont joins Matt, Jesse and Andy to talk about writing the upcoming Paddington in Peru, alcohol detox champion hornets, Shatner's double SPATS, memory not being confined to the brain, Jesse getting checked in on by local kids and Matt's oath to take up arms for the United States.

Comedian Benny Blue (@bennyblueeyes) joins Jesse, Andy and Matt to talk about brat summer transitioning into the fall of civilization, Benny's new special Live From My Mother's Funeral, Benny and Andy's Blue Lake connection, Anarchist Cookbook adolescent shenanigans, why humans are the perfect size for speed, Matt and Andy's show with the 2022-iest name ever, the best mural ever painted and its painter, Norm MacDonald's sketch artist sketch, how an asteroid got ants into farming fungi,...

Comedian and former Probably Science cohost Brooks Wheelan (@brookswheelan) joins Jesse and Andy to talk about his new special Alive In Alaska, Tony Hinchcliffe entering the election arena, cats beating babies at word association, Don't Wake Daddy, snake talk just for Brooks, the Teddy Roosevelt biography The River of Doubt, Chuck Klosterman's The Nineties, the ever-changing landscape of standup and Andy's upcoming gigs with Warsaw Poland Bros.

Comedian Jeffrey Jay (@heyjeffreyjay) joins Matt, Jesse and Andy to discuss UnCertified Fresh, the Matt Walsh-iverse of awful movies, Earth gaining a second moon, the orbital path of that object, an octopus that punches fish to make them help it hunt and choceted EEG caps for cats.

DJ Qualls (@TheOnlyDJQualls) and Kelly Blackheart (@kellyblackheart) of the Locked & Probably Loaded podcast join Matt and Jesse to talk about DJ's upcoming movie Carved, Nashville dive bars, the Ark Encounter, the Ig Nobel prize for butt-breathing, extreme aging, re-creating Mars in a lab and resurrecting the woolly mammoth.

Comedian Maronzio Vance (@maronziovance) joins Andy, Matt and Jesse to talk about Andy's upcoming ska festival and Oktoberfest polka band gigs, Taipei's innovative trash system, dating Prince-obsessed women, dogs' incredible ability to remember the names of toys, the gut-first path of Parkinson's and comedy's legendary Tribble runs.

Comedian/actress/podcaster Helen Hong (@funnyhelenhong) joins Matt and Andy to talk about peeing in pools and reservoirs, male stripper shows, Helen's excellent quiz podcast Go Fact Yourself, pre-Darth Vader David Prowse PSAs, the dye in Doritos that can make mice transparent, a SpaceX rocket punching a hole in the ionosphere, mailing poo in a box and making pyrex invisible with vegetable oil.

Writer/producer Sam Pasternack (@sampasternack) returns to the podcast to talk with Matt, Andy and Jesse about awful bar trivia, Sam's new book "Walker," the history of pedestrianism, Land's End to John o' Groats, Andy's Burning Man updates, the dilemma of trombone utility and using massive python meals to help develop new human heart medicines.

Mystery Science Theater alum, comedian and author Frank Conniff (@FrankConniff) joins the crew to talk about his new audiobook Dark Apnea.  Plus horoscope doubts! Carl Sagan predicting the future! And where dinosaur killing asteroids came from! In the patreon bonus ep we talk about saving the banana from extinction. Sign up here!

Comedian Mark Cohen (@mark_coco_cohen) joins Jesse, Andy and Matt to discuss the two aging bursts humans experience, restoring Tonka trucks, weaning crocodiles off of cane toads, Mark's video game creations, using slime mold to help map dark matter, and stock photo artists who play Lawn Mowing Simulator. and Mark's possible record-breaking stint at The Comedy Cellar in Las Vegas.

Neuroscientist-turned-comedian Isak Allen (@isakallen) joins Matt, Jesse and Andy to talk about smashing flies, using fMRI to study brain activity as it relates to music and comedy, tonal languages, the Dong Song, Neuralink, dystopian futures and Isak's new Dry Bar special Culturally Unavailable.

We've got just the prescription for everyone out there with Olympic fever: A re-release of a 2013 episode in which Matt and Andy interview David Epstein, a Sports Illustrated journalist and the author of the outstanding book The Sports Gene, along with college basketball player-turned-comedian Paul Morrissey, to discuss the field of sports genetics research and try to get to the bottom of how elite athletes are made. Enjoy!

Comedy legend Cathy Ladman (@cathyladman1) joins Jesse, Andy and Matt to talk about creepy Foundation for a Better Life billboards, cancer battles, 1970s acid, the CrowdStrike software crash, how propofol tips your brain into chaos, the merits of comedy classes, Brazilian cocaine sharks and Cathy's September 7th Vegas show.

Producer David Brown joins Jesse, Matt and Andy to talk about creating entertaining science programming, the new Peacock show The Hungry Games: Alaska's Big Bear Challenge that David produced, Rhys Darby narrated and Matt and Andy worked on, the Emmy-winning pop-science show Could You Survive The Movies?, Andy's Top Gun cameo, Fat Bear Week, Goro's pecs, a south-of-the-border Orson Welles experience, using AI to figure out the sperm whale phonetic alphabet, Larry the cat and Boris...

Comedian Todd Barry (@toddbarry) joins Matt, Andy and Jesse to talk about his new special Domestic Shorthair, an FDA ban of a citrus soda ingredient, ginger ale vs. ginger beer, the quackery of Dr. Idz, new images of an asteroid that just whizzed by Earth, Jesse's air force base food poisoning story, whether toxoplasmosis causes crazy cat lady syndrome and Jackson Galaxy's Cat Camp.

Comedian Sid Singh (@mrsidsingh) joins Andy, Jesse and Matt to talk about being a Brexit and Biden bellwether, Mozart the millenial, weird tunings, 432 Hz b******t, old-ass Washington cherries, SPATS updates, a clever way to curb rhino horn poaching, meat rice, debunking Novi's etymology and ant surgeons.

Writer/podcaster Jordan Morris (@Jordan_Morris) returns to the show to talk with Matt, Jesse and Andy about his upcoming graphic novel Youth Group, the YA genre, hawk tuah, breakdancing in the Olympics, elephants calling each other by name, wartime magicians, GPT-4 passing the Turing Test, using AI to cancel customer anger, a new stab at AI alignment and creating plasma fireballs in the lab.

Matt and Andy host a live installment of the podcast from To 29 and Beyond in Twentynine Palms featuring guests Bobcat Goldthwait, Rhys Darby, Dr. Farah Alibay and Natalia Reagan, digging into topics including indoor rocketry, opening for Nirvana, projectile bibles, the Cryptid Factor podcast, Bobcat's Bigfoot movie, 10 Million Dollar Bigfoot Bounty, Robin Williams and Koko the gorilla, Mars landers, returning samples to Earth, and Dr. Alibay's work on the upcoming NASA/JPL all-sky spectral...

Comedian, quizzer, doctor, chaser and now author Paul Sinha (@paulybengali) joins Jesse, Andy and Matt about his new memoir One Sinha Lifetime, training for quiz shows, underperforming on Taskmaster, Paul’s Parkinson’s diagnosis, how he transitioned from medicine to comedy, being outed decades after coming out, this weekend’s To 29 and Beyond, the 29 Palms scavenger hunt that Andy developed, James Webb spotting the birth of some very early galaxies, Charles Dickens the performer, what really...

Comedian, actor and host of The Tomorrow Show Ron Lynch (@ronlynch1) checks in with Matt, Jesse and Andy to talk about the groundbreaking show Home Movies, Ron's geology degree, microplastics in your balls, Terrence Howard's magnificent b******t, reducing the carbon footprint of cement, using the Sun as a giant telescope and of course To 29 and Beyond, coming to Outpost 29 June 7-8.

Comedian Omid Singh (@omid_singh) joins Jesse, Andy and Matt to talk about Omid's Lil Special, the recent additions to the To 29 and Beyond lineup, including Moshe Kasher and Natasha Leggero's Endless Honeymoon podcast and Rhys Darby, southern indifference to northern lights, Omid's dream song, Dubai construction projects, The Line in Saudi Arabia, red flags in the AI world, repurposing coffee grounds for construction projects, supercapacitors and the future of energy storage and the...

Comedian Shane Mauss (@shane_mauss) returns to the podcast in the midst of his A Better Trip tour to talk with Matt and Andy about having his van broken into, his new line of plant activated products, the connection between Amanita muscaria mushrooms and Mario and Santa, the trendiness of ketamine, a psychedelic toad venom that may have therapeutic uses (and that, of course, Shane has already tried), a wounded orangutan using a plant as medicine, and discount presale passes for To 29 and...

Comedian Sierra Katow (@sierrakatow) joins Jesse, Andy and Matt to talk about her new standup special Funt, the upcoming appearance on Roots of Comedy with Jesus Trejo, the underrated Earth to Ned, Sierra's computer science background and childhood obsession with Neopets, Andy's head-scratching interaction with Anthropic's Claude AI, deadly pathogens that are attracted to human blood, the importance of robot insurance, the security issues raised by quantum computing, online Oregon Trail, a...