The pandemic has healthcare providers pursuing innovation like never before—but they must also ensure those cutting-edge ideas and technologies deliver value to patients. We discuss this with: Antoinette de Bont, dean of the Tilburg School of Social & Behavioral Sciences at Tilburg University, the Netherlands: She discusses the BigMedilytics project—an initiative that aims to bring data science and healthcare together—and how project leaders can help team members collaborate. Christine DeVol, PMP, director of the enterprise project management team at Moffitt Cancer Center in Tampa, Florida, USA: She shares how her team—the 2021 PMO of the Year Award winner—pivoted and reprioritized its project portfolio as COVID-19 spread. DeVol also discusses a project to help connect new cancer patients to experts quickly and safely.  Key themes [01:34] Exploring new ways to use big data in healthcare [04:41] Improving collaboration  [07:22] How data science could transform patient care [09:36] How Moffitt Cancer Center adapted during COVID-19 [15:28] Ensuring innovation delivers value to patients