In this episode, Michael Love joins us to talk about the differential gene
expression analysis from bulk RNA-Seq data.
We talk about the history of Mike’s own differential expression package,
DESeq2, as well as other packages in this space, like edgeR and limma, and the
theory they are based...
In this episode, Lindsay Pino discusses the
challenges of making quantitative measurements in the field of proteomics.
Specifically, she discusses the difficulties of comparing measurements across
different samples, potentially acquired in different labs, as well as a method
she has developed...
In this episode, we learn about B cell maturation and class switching from
Hamish King. Hamish recently published a
paper on this subject in Science Immunology, where he and his coauthors
analyzed gene expression and antibody repertoire data from human tonsils.
In the episode Hamish talks about...