The status of healthcare in the US today is one of extremes — tremendous biomedical discovery along with major advances in disease prevention and treatment — and yet, America struggles with how to pay the runaway costs for even the most basic interventions. Thought leaders from Colorado’s top medical centers discuss how today’s science is pushing the boundaries of medicine and patient care — and how academic medical centers are leading the way in redefining how medicine is practiced, delivered, and valued. (Content produced by University of Colorado Anschutz Medical Campus.)