Yale Center for Clinical Investigation Yale University

Dr. Lewis has found that African-Americans who report a high rate of slights and mistreatments also show metabolic indicators that they are at risk for cardiovascular disease. Her future work will look at coping skills to help people avoid the dangerous health effects of discrimination, while also probing ways to reduce that discrimination.

Dr. Robert Sherwin draws upon his career doing landmark research in diabetes to help new investigators pursue science that improves health care. Reflecting on his role as primary investigator of Yale’s NIH Clinical and Translational Science Award, he sees a need to educate “translators,” researchers who can connect basic scientists and clinicians.

William Tamborlane’s groundbreaking research changed the way diabetes is managed, but he says that research of that kind is becoming increasingly difficult to do. As YCCI Deputy Director for Clinical Research and Director of the Office of Research Services, Dr. Tamborlane works to remove barriers for the next generation of clinical researchers.

Kathleen Uscinski of Yale’s Office of Human Research Protection is streamlining clinical research by working at Yale and with institutions around the country to find ways to ensure safety without creating unnecessary bureaucracy.

Erik Shapiro’s lab is working to manipulate dormant stem cells to migrate to sites of injury or disease so that the body can effect its own repairs. He terms this out-of-the-box approach “high risk/high reward” science.

Associate Dean for Scientific Affairs Sara Rockwell talks about the pragmatic approach that Yale takes in evaluating the effectiveness of the Yale Center for Clinical Investigation.