checkout this highly cited paper as a hosted conversation Summary This article examines the significant challenges in applying artificial intelligence (AI) to clinical healthcare. Key obstacles include the inherent limitations of machine learning, logistical hurdles in implementation, and the need for robust regulatory frameworks. The authors emphasize the importance of rigorous clinical evaluation, using metrics relevant to real-world practice and patient outcomes, to ensure AI systems are both safe and effective. Furthermore, they highlight the need to address algorithmic bias and improve the interpretability of AI models to foster trust and wider adoption. Ultimately, the successful integration of AI in healthcare hinges on overcoming these challenges to realize its transformative potential.