In this episode, CSIS Senior Associate Jeffrey L. Sturchio speaks with Gregorio (Greg) Millett, vice president at amfAR, the Foundation for AIDS Research, and the director of amfAR’s Public Policy Office, about whether we’re doing enough to underserved populations in the fight against HIV/AIDS.  Greg begins with a review of the state of the HIV/AIDS epidemic in the United States, looking at how health disparities are reflected in the patterns of infection, care, and treatment when the data are viewed through the lenses of race, ethnicity, gender, age, and geography.  He also addresses such questions as what are the key sources of risk and vulnerability that make it challenging to achieve the Ending the HIV Epidemic (EHE) goals? How has COVID-19 affected the domestic HIV epidemic? How do factors like housing instability, poverty, food insecurity, racism, stigma, and discrimination lead to disparities in access to HIV care and treatment for key populations? Why have there been lags in access to and uptake of new tools for pre-exposure prophylaxis (PrEP)? Greg also discusses parallels and differences between response to the HIV pandemic globally and domestically, as well as the implications of the situation in Ukraine for people living with HIV who are forced to leave home. The podcast concludes with his reflections on causes for optimism and hope in the continuing fight to end HIV/AIDS.