Dr. Michael von Wagner, Chief Medical Informatics Officer at University Hospital Frankfurt and a pioneer in interoperability, speaks about the importance of a seamless data exchange for personalized patient treatments and efficient health care systems.  On this episode, Dr. von Wagner joins Alex Maiersperger to discuss health data standardization, new regulations, and two pioneering data and AI projects at University Hospital Frankfurt. A team of experts came together at the hospital to integrate data from different sources into a dashboard that monitors trends in the development of antibiotic resistance, enabling optimization of treatments. In another project, they collaborate with another major university hospital and general practitioners to combine research and clinical data on rare diseases to help GPs with evidence-based diagnoses. Dr. von Wagner is optimistic about the future of health care with AI-based solutions for clinical decision support, but also explains why risks and opportunities need to be evaluated carefully. He emphasizes that the interoperability, flexibility and scalability of AI-based solutions are key to a successful future.