Broadcast from KSQD, Santa Cruz on 8-29-2024: Dr. Diana Schwarzbein explains the concept of damaged metabolism, focusing on building and using biochemicals in the body. Dr. Jeffrey Bland discusses metabolic syndrome, insulin resistance, and their widespread effects on various bodily systems. Dr. Mark Houston explores the relationship between insulin resistance, diabetes, and cardiovascular disease. Dr. David Perlmutter explains the connections between diabetes, inflammation, and neurodegenerative diseases like Alzheimer's and Parkinson's. The concept of food as information is introduced, highlighting how nutrients can influence gene expression and cellular function. The role of advanced glycosylation end products (AGEs) in aging and disease is discussed. The importance of fat cells as an endocrine organ and their impact on inflammation is explored. Mitochondrial function and oxidative stress are explained in relation to cellular health and disease. Dietary and lifestyle recommendations for reducing inflammation and improving overall health are provided by multiple speakers. The potential benefits of specific supplements like omega-3 fatty acids, vitamins C and E, and green tea extract are discussed. The speakers advocate for a more holistic, interconnected approach to medicine that addresses root causes rather than treating symptoms in isolation.