Are you tired of yo-yo dieting and struggling to achieve lasting weight loss? Have you heard about the buzz surrounding GLP-1 agonist medications like semaglutide and tirzepatide but aren't sure how to effectively incorporate them into your journey?    In today’s episode, Dr. Gus Vickery and I discuss the effective use of GLP-1 agonist medications like semaglutide and tirzepatide for sustainable weight loss. He emphasizes the need for a mindset shift, viewing these drugs as powerful tools to catalyze positive changes rather than easy fixes or crutches. Dr. Vickery explains that these medications provide leverage to implement foundational healthy habits and that the key to success lies in focusing on nutrient sufficiency, not just calorie restriction.   We also discuss concerns surrounding GLP-1 medications, such as the potential for muscle loss and the risk of regaining weight after discontinuing the drugs. He shares strategies to mitigate these issues, including resistance training, adequate protein intake, and gradual dose reduction when nearing one's goal weight.   Dr. Gus Vickery is an author, speaker, and the founder and directing physician of Authentic Health in Asheville, North Carolina. He established his practice with a commitment to delivering holistic, compassionate, and evidence-based care.   Thank you to our sponsors for making this episode possible: Quicksilver: Visit quicksilverscientific.com/nat and use code Nat for 10% off your first purchase of PushCatch® Liver Detox. Neurohacker Collective: Visit neurohacker.com/nathalie and use code NATHALIE Inside Tracker: Use NIDDAM to save 10% at https://www.insidetracker.com   Find more from Dr. Gus Vickery:  Website: https://drgusvickery.com/  Authentic Health Book: https://drgusvickery.com/book/  Instagram: @drgusvickerymd  Youtube: The Family Doctor Find more from Nathalie: YouTube: https://www.youtube.com/channel/UCmholC48MqRC50UffIZOMOQ  Join Nat’s Membership Community: https://www.natniddam.com/bsp-community  Sign up for Nats Newsletter: https://landing.mailerlite.com/webforms/landing/i7d5m0  Instagram: https://www.instagram.com/nathalieniddam/  Website: www.NatNiddam.com    Facebook Group: https://www.facebook.com/groups/biohackingsuperhumanperformance  What We Discuss:  04:00 Understanding the Power of Peptides 07:45 The Underlying Benefits of Peptides 12:59 Addressing Concerns about Side Effects 29:06 The Right Way to Use Peptides 30:06 Hormone Therapy and Peptides 34:12 Nutrient Sufficiency and Protein 41:17 The Impact of Fasting and Gut Health 45:33 Addressing Microbiome Balance 58:56 The Pace of Fat Loss and Patience 59:42 Pushing Through Plateaus and Delicate Nervous System 01:07:13 Managing Hormetic Stress and Resting the Nervous System 01:09:00 Choosing Carbs or Fats and Individualization   Key Takeaways: Peptides can be a powerful tool for improving body composition and metabolic health. It is important to understand the proper use of peptides and not rely on them as a quick fix or easy way out. Peptides have a range of benefits, including improving insulin sensitivity and reducing fatty liver disease. Concerns about side effects and risks should be weighed against the potential benefits and individual circumstances