Could the root cause of Parkinson's disease be hiding in your gut?   In this Longevity Podcast episode, I am joined by Martha Carlin, founder of The BioCollective and BiotiQuest, to explore the role of lipopolysaccharides (LPS) – cellular debris from harmful bacteria – in Parkinson's disease and other chronic conditions.    We dive into the importance of the microbiome in overall health, the connection between constipation and Parkinson's, and the potential impact of probiotics in mitigating LPS-related issues. We also explore the benefits of cold showers, cold plunges, and cryotherapy in signaling microbes and the potential of AI in accelerating learning and understanding the complexities of the microbiome.    Martha Carlin, a former business turnaround expert turned citizen scientist, has emerged as a pioneering force in microbiome research and Parkinson's disease studies since her husband's diagnosis in 2002. After teaching herself chemistry, physics, biochemistry, and microbiology, she founded The BioCollective in 2015, creating one of the world's first fecal banks to accelerate microbiome research, and later developed BiotiQuest, a line of innovative probiotics. Her groundbreaking work has led to collaborations across multiple scientific disciplines and speaking engagements at prestigious venues, including The White House 2016 Microbiome Initiative.    Shop BiotiQuest formulas at https://biotiquest.com/ and use code NAT15 to save.    Thank you to our sponsors for making this episode possible:                                                                                                                                                           Young Goose: First order? Shop here Subsequent orders? Shop here and use code 5NAT. Neurohacker: Shop at http://www.qualialife.com/nathalie and use code NATHALIE to save BEAM Minerals: Go to https://www.beamminerals.com code NAT20 to get 20% off your order   Find more from Martha Carlin:  Website: MarthasQuest.com, TheBioCollective.com, https://biotiquest.com/    Find more from Nathalie: YouTube: https://www.youtube.com/channel/UCmholC48MqRC50UffIZOMOQ  Join Nat’s Membership Community: https://www.natniddam.com/bsp-community  Sign up for Nats Newsletter: https://landing.mailerlite.com/webforms/landing/i7d5m0  Instagram: https://www.instagram.com/nathalieniddam/  Website: www.NatNiddam.com    Facebook Group: https://www.facebook.com/groups/biohackingsuperhumanperformance    What We Discuss: 07:39 The Relevance of LPS and the Microbiome to Various Diseases 14:19 The Bio Collective Research 22:05 Understanding LPS and its Effects on the Gut 28:25 The Role of Small Intestinal Bacterial Overgrowth 35:13 The Effect of Cold on LPS in the Gut 43:29 The Potential of AI in Microbiome Research 50:46 The Biotic Quest Line of Probiotics 57:03 The Effects of Glyphosate on the Gut Microbiome