Continuing education episode! Granulocyte concentrate has been around for as long as apheresis platelets, but the product has come into and out of favor repeatedly over the years. While the most recent randomized trials were disappointing, Dr. Ron Strauss believes a closer look at the data from the famous "RING Study" convinces him that if we transfuse a "modern," high-dose granulocyte concentrate, the results can be very positive! Let's look together at the history and future of granulocyte transfusion. This episode is eligible for free CME and SAMs/CC credit for physicians and P.A.C.E. contact hours for laboratorians through Transfusion News Continuing Education on Wiley Health Learning.