Please visit answersincme.com/QMD860 to participate, download slides and supporting materials, complete the post test, and obtain credit. In this activity, an expert in cardiology discusses the management of elevated low-density lipoprotein (LDL) cholesterol in patients with severe familial hypercholesterolemia (FH). Upon completion of this activity, participants should be better able to: Identify patients with FH; Describe the clinical impact of early and intensive treatment for patients with severe FH, including homozygous FH (HoFH); and Discuss the clinical profiles of novel strategies to reduce LDL cholesterol in patients with severe FH.