In this episode, Dr Libby Sampey interviews Dr Catriona Kyle about adrenal insufficiency and steroid replacement. They discuss the different types of adrenal insufficiency and relevant physiology before exploring recognition, investigations and diagnosis, and links to other autoimmune diseases. They go on to discuss management including ‘sick day rules’, and patient follow-up. Dr Catriona Kyle is a Consultant Endocrinologist at the Western General Hospital in Edinburgh, and has a PhD in steroid physiology from the University of Edinburgh. Dr Libby Sampey is a member of RCPE’s Trainees and Members’ Committee podcast team and a Foundation Year Doctor. -- Links -- Society for Endocrinology - Adrenal Crisis Information https://www.endocrinology.org/clinical-practice/clinical-guidance/adrenal-crisis/ Diagnosis and Treatment of Primary Adrenal Insufficiency: An Endocrine Society Clinical Practice Guideline (Bornstein et al., 2016) https://doi.org/10.1210/jc.2015-1710 Society for Endocrinology https://www.endocrinology.org/ Recording date: 8 June 2023 -- Follow us -- https://www.instagram.com/rcpedintrainees https://twitter.com/RCPEdinTrainees -- Upcoming RCPE Events -- https://events.rcpe.ac.uk/ Feedback: [email protected]