In this episode of the Crazy Wisdom Podcast, Stewart Alsop interviews Delian Asparouhov, co-founder and president of Varda. They discuss the science and commercial potential of manufacturing pharmaceuticals in microgravity, the regulatory and technical challenges of space missions, the future of space colonization driven by economic activities, and the advancements in propulsion technologies. Delian also shares insights on the importance of the U.S. space economy, the potential of lunar mining, and his long-term vision for space exploration. For more updates on Varda, follow their corporate Twitter at @vardaspace. Check out this GPT we trained on the conversation! Timestamps 00:00:00 - Introduction and initial discussion about pronouncing Delian Asparouhov's last name. Delian talks about the terminology for space laboratory. 00:05:00 - Delian explains the advantages of manufacturing pharmaceuticals in microgravity and the science behind it. Analogy of cooking in a kitchen is used to describe the process. 00:10:00 - Discussion on the historical background of pharmaceutical manufacturing in space. Delian talks about the involvement of NASA and big pharmaceutical companies. 00:15:00 - The transition from proof of concept to commercialization of space manufacturing. Delian explains the regulatory challenges faced with FAA for launching and reentry. 00:20:00 - Coordinating with multiple parties for successful space missions. Discussion about the future potential of landing missions outside the United States, specifically mentioning Australia. 00:25:00 - Delian discusses the current space economy, SpaceX's impact, and the dominance of the United States in mass to orbit. 00:30:00 - The vastness of space and how much space there is for satellites and other objects. Delian mentions the Lagrangian points as useful waypoints in space. 00:35:00 - Speculation about long-term human colonization in space driven by economic activities. Delian talks about the potential of lunar surface mining and manufacturing. 00:40:00 - The possibility of large-scale manufacturing on the moon and the resources available there. Delian explains the importance of economic activity for space colonization. 00:45:00 - Discussion on propulsion technologies, including electric propulsion and the future potential of warp drives. Delian explains the physics behind various propulsion methods. 00:50:00 - Delian's thoughts on the philosophical aspects of the universe and the laws of physics. He reflects on the fortuitous conditions that led to life on Earth. 00:55:00 - The role of quantum mechanics in modern technology. Delian mentions that while quantum mechanics influence technologies like semiconductors, they haven't directly influenced Varda's work yet. Key Insights 1-The Advantages of Microgravity for Pharmaceutical Manufacturing: Delian Asparouhov explains how the microgravity environment of space allows for unique chemical reactions and crystal formations that are impossible on Earth. By removing the influence of gravity, substances can mix and react more uniformly, leading to potentially better and more stable pharmaceutical products. 2-Historical Context and Industry Involvement: The idea of using space for manufacturing isn't new. Delian discusses how major pharmaceutical companies like Merck and Bristol Myers Squibb, as well as NASA, have been experimenting with microgravity for decades. Varda's approach builds on this history but aims to commercialize the process using modern, cost-effective technology. 3-Regulatory Challenges and Achievements: Varda faced significant regulatory hurdles, particularly with the Federal Aviation Administration (FAA), to secure permissions for launching and reentering spacecraft. Delian highlights the complexity of coordinating with multiple parties, including the military and commercial partners, to ensure mission success and safety. 4-The Dominance of the U.S. in the Space Economy: Delian emphasizes that the United States i