Dr. Anne Bunner discusses research on how genetics and traumatic brain injury (TBI) interact to impact Alzheimer’s disease risk. Publication discussed: Hayes JP, Logue MW, Sadeh N, et al. Mild traumatic brain injury is associated with reduced cortical thickness in those at risk for Alzheimer's disease. Brain. 2017;140(3):813-825. doi: 10.1093/brain/aww344 CUBIST is a podcast for health care providers produced by the Traumatic Brain Injury Center of Excellence. We discuss the latest research on traumatic brain injury (TBI) most relevant to patient care. For more about TBI, including clinical tools, go to www.health.mil/TBICoE or email us at [email protected]. The views, opinions, and/or findings in this podcast are those of the host and subject matter experts. They should not be construed as an official Department of Defense position, policy, or decision unless designated by other official documentation. Our theme song is “Upbeat-Corporate’ by WhiteCat, available and was used according to the Creative Commons Attribution-Noncommercial 4.0 license.