In this episode, Sam Ashoo, MD interviews Prayag Mehta, MD and Joshua Kern, MD - two of the authors of the June, 2022 EMP article on Procedural Sedation and Analgesia in the Emergency Department. Listen to the discussion to hear more about the emergency medicine approach to sedation in adults and pediatrics ! Procedural Sedation and Analgesia in the Emergency Department https://www.ebmedicine.net/topics/emergency-procedures/emergency-medicine-procedural-sedation EMplify - June 2022 Episode Outline: Procedural sedation and analgesia (PSA): terminologyLevels of sedationMinimalModerateDeepGeneral anesthesiaPrehospital careED care: patient assessmentASA class system ComplicationsEquipment needed (Table 1) Larson maneuver (Figure 2)Procedural techniqueCurrent ACEP and AAP recommendations Data for 1- or 2-physician sedation Preprocedural fastingDo we even need to consider this in PSA?CapnographyOxygen supplementationPreprocedural opioids Preprocedural sedatives Anticholinergics Antiemetics Treatment (Table 2) Fentanyl Remifentanil Midazolam Nitrous oxide PropofolKetamineKetofolEtomidateReversal agentsNaloxoneFlumazenilSpecial populationsPediatricsPregnancyGeriatricsCutting edge Dexmedetomidine https://foamed.ebmedicine.net/rapid-reference/procedural-sedation-medications/