In this episode, Sam Ashoo, MD, and TR Eckler, MD, discuss the December 2022 Evidence-Based Urgent Care article on Influenza in Urgent Care.Epidemiology* Historical data* Since COVID, tracking "influenza-like illness" has been complicated* Influenza deaths and age* Annual mortality OutbreaksTransmissionClassification* Influenza A, B, and C* Hemagglutinin and neuraminidase subgroups* Antigenic drift and shiftPathophysiology* Transmission* Incubation * Secondary infection* H3N2Vaccines* Egg-based, cell-based, and recombinant influenza vaccines* CDC recommendations* Patients aged >65 yearsDifferential DiagnosisComplications Testing* When is it indicated? * What types of tests are available? * Testing in periods of low and high prevalence Treatment* High-risk conditions that suggest treatment * Antiviral medications * Oseltamivir: NNT and NNH* Resistance patternsBilling and Coding