South African farmers must comply with the Hazardous Substances Act of 1973 when using pesticides, especially Group 1 Category B products.   In this article, we explore the details of Group 1 Category A and Group 1 Category B hazardous substances, focusing specifically on agricultural remedies and how they are regulated under Act No. 15 of 1973.   Hiresh Ramanand, a stewardship specialist at CropLife South Africa, and Quade Sing Jam, a compliance specialist at CropLife South Africa, provide clarity on the practical implications of this legislation for farmers.