Today, Paul and Mike unpack their opinions about lipids. They talk about true risk for cardiovascular disease, primary versus secondary prevention, lipid lowering drugs, and share their thoughts on a recent podcast episode with Peter Attia. *Produced by Mountain Valley Media 00:06:08 Blood markers & imaging techniques of metabolic function  00:14:38 Gene mutations 00:20:28 LDL & Plaque burden 00:27:23 Money in statins 00:31:38 Downsides of lowering LDL 01:21:23 The downsides of popular cholesterol lowering drugs 01:41:07 Should we fear heart attacks? 01:45:23 PCSK9 Inhibitors 01:52:43 Risk profile of Statins  01:53:02 Risk vs. reward of Ezetimibe 02:04:02 Primary vs. secondary prevention Resources: Debunking Sugar Claims: What Dr. Lustig Got Wrong On The Huberman Podcast: https://www.youtube.com/watch?v=JcEmSgbMfco&t=2933s Work With Mike: https://mikefave.com/