Acute appendicitis is a medical emergency characterised by the sudden onset of inflammation in the appendix. As one of the leading causes of abdominal pain that necessitates surgical intervention, appendicitis can occur at any age, though it is most common in adolescents and young adults. The condition is primarily caused by a blockage in the appendix, which leads to bacterial infection, swelling and increased pressure. If left untreated, acute appendicitis can progress to life-threatening complications such as perforation, peritonitis and sepsis. Due to the non-specific symptoms, particularly in the early stages, diagnosing appendicitis can be challenging. Prompt recognition and treatment, typically through surgical removal of the appendix, are critical to preventing complications and ensuring a swift recovery. In this episode, Dr Roger Henderson looks at the clinical presentation, diagnosis and management of acute appendicitis, highlighting its significance as a common yet potentially dangerous medical condition.Access episode show notes containing key references and take-home points at: https://gpnotebook.com/en-GB/podcasts/gastroenterology/ep-129-acute-appendicitis (https://gpnotebook.com/en-GB/podcasts/gastroenterology/ep-129-acute-appendicitis).Did you know? With GPnotebook Pro, you can earn CPD credits by tracking the podcast episodes you listen to. Learn more (https://gpnotebook.com/en-GB/gpnotebook-pro).