Nicholas Thorne is building Squarespace for the AI age. It’s called Audos, and it’s an AI chatbot to help any entrepreneur go from idea to: - Pitch deck - Working website - Custom GPT - User interviews with real customers All in just a few minutes. And he did it using ChatGPTapp. It’s AI all the way down—and it’s one of the most impressive AI businesses I’ve ever seen. Nicholas is a general partner at Prehype, an incubator that launched Barkbox and Ro Health. It’s also where I started...

Antidepressants changed my life. I have OCD and antidepressants did what nearly a decade of therapy, meditation, and supplements couldn’t: they allowed me to live my life without being in a 24/7 spiral. (Bonus: they actually made therapy and meditation far more helpful once they started to work.) I think antidepressants are seriously misunderstood. Yes, they blunt negative emotions. But they also operate on personality and sense of self: they can make you bolder, less sensitive to failure,...

You can build and run a one-person internet business that earns half a million in annual revenue—with AI. Ben Tossell showed me exactly how in this episode. Ben is the founder of Ben’s Bites—one of the best daily AI newsletters out there, which I love reading every day—and an investor in a number of promising early-stage AI startups. Ben is also an experienced founder whose no-code platform Makerpad was acquired by Zapier. I think Ben is really good at starting profitable internet...

I made the greatest trade of my life with Jesse Beyroutey in 2019. We bought Nvidia shares when they were trading at $33. They’re worth nearly $800 today. I sat down with Jesse to top that trade in 90 minutes using Gemini Pro 1.5’s incredible 1 million token context window—and make a $1,000 trade live on the show.  Jesse is a managing partner at IA Ventures, a $600 million venture fund with seed investments in companies like Wise and Digital Ocean. He’s also a very close friend and one of...

You can break into Hollywood with a movie you made alone in your room. Dave Clark can show you exactly how in 60 minutes. He’s a film director with a body of work that includes both feature films and commercials for brands like Google. His latest achievement is a stunning sci-fi short that got Hollywood’s attention, one that Dave made exclusively using AI.  Dave and I make a movie live on this episode, iterating from rough ideas to a real motion picture in 1 hour. It’s a noir short...

Are you a curious person with a lot of ideas and little time? Anne-Laure Le Cunff can show you how to do it all. Anne-Laure is the founder of one of my favorite internet communities for curious minds, Ness Labs, a prolific writer, and a neuroscience PhD candidate. She’s also writing a book, Liminal Minds, that’ll be out later this year. And she said that the reason she can run a business, write a book, and do a PhD all at the same time is ChatGPT. Anne-Laure is one of the busiest people I...

Steph Smith is the host of the a16z podcast and a prolific online creator.  Steph sees the internet through a high-definition lens that gives her a deep understanding of what people want.  She can isolate a clear signal from the noise, which she uses to build wonderfully creative, useful things.   In this episode, I dive deep with Steph on how she uses the internet and AI to unearth emerging trends and validate business ideas. I pitch Steph two potential companies on the show, and we use...

You can build a video game without writing a single line of code. Logan Kilpatrick and I use ChatGPT and GPT Builder to make our own video game in less than 60 minutes—live on this show.  Logan is OpenAI’s first dev relations and advocacy hire and is committed to empowering more people to build using AI. It’s only fitting that we explore the depths of our own creativity by making a video game with GPT Builder—we start with a rough idea and iterate all the way up to a functional video game...

Dr. Gena Gorlin⁠ is a clinical psychologist at UT Austin whose goal is to raise the ceiling on human potential.  I sat down with her to discuss how @ChatGPTapp has become a key tool in her quest for radical self-betterment. In this episode, she feeds ChatGPT a list of her old journal entries, and it conducts the most thorough and insightful annual review and goal-setting session you’ve ever seen:  It writes a personal biography for her, unpacking themes and key questions from each year...

Tyler Cowen is an economist who has been thinking about the impact of technology on life, work, and the economy for the past decade.  He is a prolific writer behind the leading economic blog Marginal Revolution, a professor of economics at George Mason University, and the author of 17 books.  In this episode, I dive deep with him on how ChatGPT will change the economy, and how he uses it in his own life. We get into: How ChatGPT makes him smarter How he uses it for deep reading and...

David Perell is one of the best known internet writers of his generation.  He’s amassed almost a half million followers on X, hosts the popular podcast How I Write, and founded Write of Passage, which has taught thousands of students how to be digital writers. We go deep on using ChatGPT to:  Doing deep reading of old books Finding anecdotes that spread Better understanding your taste Finding your heroes Understanding your blind spots as a leader Unpacking the strategy of your...

This show might be a first in the history of podcasts: Researcher Geoffrey Litt and I built an app together using ChatGPTapp and Replit in under 60 minutes—while we talked. We wanted to show how AI and ChatGPT change who gets to build software and how they usher in a world where everyone can modify and remix the apps they use every day. So we did it live, and ChatGPT delivered a working prototype at the end of the episode. It was a tiny glimpse of the future—and it pushes the boundaries...

I spent an hour and a half with Nathan Labenz, who went deep with me on using ChatGPT to: Save days of time on programming projects Boost his creativity Provide access to limitless expertise We covered both the practical and philosophical, including: Using AI in copilot versus delegation mode How ChatGPT relieves the hidden drudgery of creative work Prompting techniques to maximize your thought partnership with ChatGPT How he believes AI will do for cognitive...

TL;DR: Today we’re releasing a new episode of our podcast How Do You Use ChatGPT? I go in-depth with Notion research engineer Linus Lee on how he uses ChatGPT and Notion AI to maximize creative control. Watch on X, YouTube, or Spotify.You might think that being an AI researcher would mostly involve solving complicated programming problems and thinking through mathematical equations. Instead, a big part of the job is rewriting parts of your prompts in ALL CAPS in order to make sure the AI...

How Nat Eliason uses ChatGPT to write books: Nat Eliason is a shape-shifter. He’s a writer with a book deal from Random House, a crypto trader, a Roam Research aficionado, a marketer, a book podcaster, a parent, and a seed oil iconoclast. He's amassed thousands of newsletter subscribers, 70,000 followers on X, and 110,000 on TikTok. His secret weapon for all of his exploring? ChatGPT. Nat took me through why he uses it every day for his work and his life. In this interview we talk about...

About the show I believe that ChatGPT is the most important creative tool of the decade. I think it can help us write better, create art, efficiently ship products, build great businesses, make smart decisions, and even learn something about ourselves,. But it’s still so early. Most of us don’t even really know how to use ChatGPT. We have a feeling that it’s powerful, interesting, and important—but we haven’t figured out how to incorporate it into our lives. There are a few people, though,...