Pediatric pain is under-recognized and under-treated throughout the world. Recently, a Lancet Child & Adolescent Commission was formed to address this critical problem. In this PRF podcast, three co-authors on the Commission, Paula Forgeron, RN, MN, PhD; Richard Howard, FFPMRCA; and Tonya Palermo, PhD, meet virtually with PRF Correspondent Wendy Gaultney to discuss the origins of the Commission’s work, the problem of pediatric pain, and the way forward to improve the lives of children with pain.