As the pace of technological change continues to accelerate, driven by advancements in generative AI, machine learning, and quantum computing, organisations and enterprise have been faced with increasing uncertainty. Amongst this uncertainty, climate change, geopolitical competition and demographic changes continue to pose challenges to society and businesses across Europe. In this panel discussion, expert speakers discuss how horizon-scanning tools can assist and support policymakers, citizens, and organisations in making sense of, and addressing, uncertainty as well as identifying potential opportunities arising. This panel has been organised in conjunction with Enterprise Ireland, and the Department of Enterprise, Trade and Employment. About the Speaker: Larry O'Connell is the Director of the National Economic and Social Council. Aaron Maniam is a Fellow of Practice and the Director of Digital Transformation Education at the University of Oxford’s Blavatnik School of Government. Soile Ollila is the Foresight Manager at Business Finland. Alessandra Colecchia is the Head of Science and Technology Policy at the OECD.