Innovation technologique Liliane Bettencourt (2022-2023) - Lydéric Bocquet Collège de France Année 2022-2023 Colloque - La nanofluidique à la croisée des chemins : New Approaches in Nanofluidics: Carbon Nanotubes Mechanical Resonators I will present our work in the direction of combining mechanical resonator and nanofluidic channel with a carbon nanotube. First, I will discuss how mechanical resonators will allow to answer, experimentally, open questions in the nanofluidic community about the structure of water, the phase diagram and the mechanism behind the fast flow observed in carbon nanotube. Second, I will show that SU8 microfluidic allows to combine antagonist worlds of fluidics (ambient pressure) and mechanics (secondary vacuum). Such devices can sustain large water pressure up to 5 bars and do not degrade over time. Porosity of SU8 is equal or better to PDMS, the standard in fluidics. Moving to carbon nanotube nanomechanical resonators, I will show that they exhibit exquisite mass sensitivity down to 70 yg, even at room temperature. This feature is observed in several devices, making it a reliable asset. I will discuss the limitations to the sensitivity in terms of thermomechanical noise, frequency fluctuations, etc. Finally, I will demonstrate that electrons in carbon nanotubes can distinguish water adsorbed on the surface of the nanotube from water confined inside the nanotube. Again, this feature is reproducible in several devices and independent of the metallicity of the nanotube. Adrien Noury Adrien Noury received his PhD in Physics (Photonics and Material Sciences) in 2014 from Univ. Paris Sud, on carbon nanotubes hybrid photonics. He then joined the group of Adrian Bachtold in ICFO Barcelona to work on quantum electromechanics with graphene drums, and later Helium superfluids on nanotube mechanical resonator. Since 2017 he is CNRS researcher in L2C, Montpellier, where he started and led the Nanomechanics group. His research focuses on harnessing the exceptional sensitivity of nanotube mechanical resonators in order to adress challenging questions in Physics.