States are increasingly able to weaponize their centralized positions within global informational and economic networks for strategic purposes. Contrary to traditional arguments that globalization and economic interdependence will lead to increasing international cooperation, this episode discusses how states can leverage global networks to engage in coercion. The episode discusses broader trends as they relate to global sanctions, the relationship between foreign policy and private sector interests, and American economic coercion vis-à-vis Iran, China, and Russia.