In this Q&A, JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS, and Bernard S. Chang, MD, MMSc, a neurologist and dean for medical education at Harvard Medical School, discuss how AI will change medical education, admissions, and teaching the future generation of physicians and clinicians. Related Content: AI Will—and Should—Change Medical School, Says Harvard’s Dean for Medical Education Transformation of Undergraduate Medical Education in 2023