Screen use by children is common and can affect child development, with effects varying by age and developmental domain. JAMA Pediatrics Editor in Chief Dimitri Christakis, MD, and JAMA Pediatrics Associate Editor Alison A. Galbraith, MD, discuss evidence about screen use across childhood and strategies to reduce negative impacts with Sheri Madigan, PhD, RPsych, of the University of Calgary, Calgary, Alberta, Canada. Related Content: Screen Time at Age 1 Year and Communication and Problem-Solving Developmental Delay at 2 and 4 Years