Dr. Hoyme presented the 2008 Anthony B. DeFeo Lecture in Speech-Language Pathology on September 5, 2008. Dr. Hoyme is Professor and Chair of the Department of Pediatrics at the Sanford School of Medicine of The University of South Dakota and Chief Medical Officer of Sanford Children’s Hospital in Sioux Falls. Until 2007, Dr. Hoyme serves as Professor and Chief of the Division of Medical Genetics and Associate Chair of the Department of Pediatrics at the Stanford School of Medicine in Palo Alto, CA. The Anthony B. DeFeo Lecture in Speech-Language Pathology lecture series was established to honor the continuing outstanding career of Dr. DeFeo in clinical teaching and mentoring in speech-language pathology at the University of Arizona. Speakers in this lecture series are chosen to embody the educational and personal spirit of Dr. DeFeo, including his academic rigor, pervasive creativity, dedication to students, support of evidence-based treatments for clients, and upbeat and strong advocacy for the blending of basic science with clinical science and art.