Abstract: One of the great frontiers of contemporary science is exploration of the mind. The brain embodies our individual identities as well as our ability to cooperate with others to understand the remaining mysteries of our universe. It is composed of billions of cells, the connections amongst which capture and preserve unique experiences. Over the past half-century, ideas about the aging brain have evolved away from it being an organ of passive deterioration towards the realization that it is capable of dynamic adaptation and high levels of function well past 100 years. One question remains — can we all achieve this?