On February 15, 2023, Social Science Matrix was honored to host Mariano-Florentino Cuéllar, President of the Carnegie Endowment for International Peace, for a Matrix Distinguished Lecture entitled "Reimagining Global Integration." Abstract Whether they live in vast cities or rural villages, people in virtually every corner of the world have experienced enormous growth in cross-border economic, political, and social connections since World War II. This latest chapter in the story of transnational activity has coincided with enormous changes in the well-being of billions of people. As China gained access to global markets and its share of worldwide trade increased eight-fold in a single generation, for example, the percentage of its population living in extreme poverty plunged from 72 percent in 1990 to 14 percent in 2010. Global life expectancy has risen from less than 47 years in 1950 to 71 years in 2021, and the male-female gap in primary and secondary schooling globally has almost disappeared. But increased cross-border trade, migration, flows of information, and political ties have also engendered an intense backlash to “globalization” and related concepts. Today, at a time of major geopolitical upheaval and technological change, policymakers and the public are vigorously debating the merits of domestic policies suitable for an interconnected world. They are exploring new trade and migration rules, reviving strategies for national industrial and technological development, and reflecting on the lessons of 1990s-style globalization for international law and institutions substantially influenced by the United States. Discussions of “reshoring” supply chains and United States-China economic “decoupling” are just two examples of rising concerns in Washington about cross-border ties. Yet global cooperation remains vital to solving many of humanity’s most urgent challenges: mitigating and adapting to climate change, harnessing technology for the benefit of humanity while taming its risks, reducing poverty, and preventing violent conflict. By better understanding the long-simmering conflicts over global cooperation and integration, policymakers and civil society can further develop the ideas, institutions, and coalitions necessary to create a stable foundation for a more reflective version of global integration: one that addresses the connections between economic well-being and security, and better aligns domestic realities with international norms to tackle the pressing issues of our time. About the Speaker A former justice of the Supreme Court of California, Mariano-Florentino Cuéllar served two U.S. presidents at the White House and in federal agencies, and was a faculty member at Stanford University for two decades. Before serving on California’s highest court, Justice Cuéllar was the Stanley Morrison Professor of Law, Professor (by courtesy) of Political Science, and director of the Freeman Spogli Institute for International Studies at Stanford. In this capacity, he oversaw programs on international security, governance and development, global health, cyber policy, migration, and climate change and food security. Previously, he co-directed the Institute’s Center for International Security and Cooperation and led its Honors Program in International Security. While serving in the Obama White House as the president’s special assistant for justice and regulatory policy, he led the Domestic Policy Council teams responsible for civil and criminal justice reform, public health, immigration, transnational regulatory issues, and supporting the Quadrennial Homeland Security Review. He then co-chaired the U.S. Department of Education’s Equity and Excellence Commission, and was a presidential appointee to the Council of the Administrative Conference of the United States. As a California Supreme Court justice, he oversaw reforms of the California court system’s operations to better meet the needs of mill