During the peak of the most recent tech upswing, downtown San Francisco was booming. Now, after the pandemic and a new round of tech layoffs, commentators fear that the so-called “doom loop” has come to valuable commercial real estate. While boom and bust cycles are not new to The City, what can we learn from the struggles of commercial real estate? Recorded on October 31, 2023 at UC Berkley's Social Science Matrix, this panel featured a discussion of the current state of commercial real estate in San Francisco — and what lies ahead. Panelists include Ted Egan, Chief Economist of the City and County of San Francisco; Nicholas Bloom, the William Eberle Professor of Economics at Stanford University; and Nancy Wallace, the Lisle and Roslyn Payne Chair in Real Estate Capital Markets at Berkeley Haas. Amir Kermani, Associate Professor of Finance and Real Estate at the Haas School of Business and Research Associate at the National Bureau of Economic Research, moderated. This panel was co-sponsored by Global Metropolitan Studies (GMS), Haas School of Business, the Berkeley Economy and Society Initiative (BESI), and the Fisher Center for Real Estate & Urban Economics. A transcript is available at https://matrix.berkeley.edu/research-article/boom-to-doom/