Devon Stonerock, PharmD, Uzo Abajue, PharmD and Divya Khandekar, PharmD describe cytokine release syndrome (CRS), the literature surrounding CRS and options for CRS management. For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes. You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.