What Have We Learned from the Brain Map Project So Far? with Tom Nowakowski, UCSF
Listen now
Description
After ten years, the human brain mapping project has achieved some major milestones, says Tom Nowakowski, a researcher at UCSF, on today’s program.  He says that mapping the brain is a “moon shot” easily on par with the Human Genome Project.So much of biology is basic quantification.  Brain scientists are beginning to quantify how many kinds of brain cells there are.  They are learning more about the function of various cells such as glial cells..  And they are developing a common language with each other.  A few years ago, if you put two brain scientists in a room together, they would not know how to speak to each other.One of the major technologies that have enabled this new quantification and characterization of the human brain is spatial genomics. Tom and other scientists have learned that there are 5,000 transcriptomic clusters that they associate with cell type. '“If you told me ten years ago when I was finishing my Ph.D. that one day we’d be making real progress on neurological and neuropsychiatric disorders without having to rely on a mouse model.  I would think it was unthinkable.  Here we are; we finally have technologies where you don’t need transgenic mouse models to make progress.  That is just terribly exciting.” This is a public episode. If you’d like to discuss this with other subscribers or get access to bonus episodes, visit www.mendelspod.com/subscribe
More Episodes
Coming from the field of digital pathology, Joachim Schmid has a unique perspective on the evolution of multi-omics.  Schmid was recently appointed as Vice President of Multiomics Data Solutions at Illumina.In this episode, Theral dives into the burgeoning field of multi-omics—integrating data...
Published 11/21/24
Published 11/21/24
Dr. Mark Lewis is a well known GI oncologist at Intermountain Health in Salt Lake City, Utah. Gifted with a passionate communication style, he has over 93,000 Twitter followers. Next month, he will live-tweet his upcoming colonoscopy.   In this episode, Dr. Lewis joins Theral in our ongoing...
Published 11/14/24