Dr. Emeran Mayer is one of the world's leading experts on the gut microbiome and gut-brain interaction. The discussion dives deep into how our gut health shapes our overall health and wellbeing, the role of diet, stress, environment, and lifestyle influencing our microbiome, and how understanding this can aid us to become better versions of ourselves. Dr. Mayer also shares some intriguing revelations about potential future perspectives relating to microbiome science. (00:00) Introduction and Welcome (02:10) Interview with Dr. Emeran Mayer (03:24) The Gut-Brain Connection (06:39) The Impact of Gut Microbiome on Human Behavior (08:49) The Evolution of Gut Microbiome (10:57) The Development of Microbiome in Newborns (16:47) The Role of Microbiome in Medicine (22:53) The Impact of Fasting on Microbiome (25:38) The Role of Microbiome in Drug Metabolism (31:04) Understanding Irritable Bowel Syndrome (IBS) (44:56) The Role of Microbiome in Pain Management (48:40) Experience with Indian Guru and Mindfulness (48:52) Mindfulness-Based Therapy and Chronic Pain (49:38) The Role of Salient System in Pain Perception (50:44) The Impact of Mindfulness on the Central Autonomic Nervous Network (50:54) The Influence of Mindfulness on the Default Mode Network (51:27) The Role of Anticipation in Chronic Pain (51:33) The Comparison of Human Brain and Self-Driving Cars (52:08) The Origin of Mindfulness-Based Strategies (53:07) The Role of Open-Mindedness in Meditative Practices (53:40) The Importance of Awareness and Education in Pain Management (54:12) The Therapeutic Role of Knowledge (54:37) The Impact of Stress on Gut Function and Microbes (55:14) The Potential Role of Psychedelics in Pain Management (55:41) The Future of Psychedelics in Medicine (55:45) The Impact of Psychedelics on the Gut and Microbes (58:21) The Potential of Psychedelics as a Curative Intervention (59:38) The Impact of Antibiotics on the Microbiome (01:12:07) The Role of Early Programming in Autoimmune Diseases (01:17:51) The Role of Probiotics and Prebiotics in Microbiome Health (01:18:18) The Impact of Diet and Lifestyle on the Microbiome (01:23:38) The Future of Microbiome Research (01:29:31) The Importance of Public Communication in Microbiome Research (01:29:58) Conclusion and Final Thoughts Dr. Emeran Mayer's Website: https://emeranmayer.com/ Dr. Mayer's Cookbook - Interconnected Plates - https://emeranmayer.com/product/interconnected-plates/ The Mind-Gut-Immune Connection: Understanding How Food Impacts Our Mind, Our Microbiome, and Our Immunity - https://www.amazon.com/dp/0063014793?ref_=cm_sw_r_cp_ud_dp_QRHEQ26N5PDT8Q5EC8F3 The Mind-Gut Connection: How the Hidden Conversation Within Our Bodies Impacts Our Mood, Our Choices, and Our Overall Health - https://www.amazon.com/Mind-Gut-Connection-Conversation-Impacts-Choices/dp/0062376551/ref=sr_1_1?ie=UTF8&qid=1462734526&sr=8-1&keywords=emeran+mayer The Performance Initiative Podcast was born out of the conviction that we all have room to improve. We all have boundless potential if we have the will and the tools to unlock it.  At the Performance Initiative, we are dedicated to finding those tools, sharing them with you, and trying them out for ourselves.  A few weeks after each episode, Zinovy and Grant report their experiences trying to put into practice what they have learned from each guest. Social & Website Website: https://www.performanceinitiativepodcast.com/ Instagram: https://www.instagram.com/performanceinitiative TikTok: https://www.tiktok.com/@performanceinitiative