Forty years ago, when James Allison had just gotten his PhD in biochemistry, he was intrigued by this far-out idea that was floating around about a new way to treat cancer. The idea—dubbed cancer immunotherapy—was to train the body’s immune system to attack cancer cells—the same way this system already goes after bacteria and viruses. He was one of the few people who actually believed it could work. In today’s episode, Allison—an alumnus of the University of Texas at Austin and the chair of immunology at MD Anderson Cancer Center in Houston—talks about the uphill climb to make cancer immunotherapy a reality. He also shows off his mad harmonica skills. Check out Allison playing harmonica with his band the Checkpoints: https://youtu.be/bsLwOAImzCs And check out his performance with the legendary Willie Nelson: https://www.houstonchronicle.com/local/prognosis/article/Willie-Nelson-shares-stage-with-Houston-cancer-6886561.php About Point of Discovery Point of Discovery is a production of the University of Texas at Austin's College of Natural Sciences. You can listen to all our episodes at @point-of-discovery . Questions or comments about this episode, or our series in general? Email Marc Airhart at mairhart[AT]austin.utexas.edu