Presenting a recorded conversation from AGBT, where we engage in dialogue with two esteemed guests from the University of Queensland. Collaborating in the realm of virology, they possess a distinctive and invaluable collection of samples—the ones from the 1918 Spanish flu. In this episode, discover the compelling reasons behind the partnership between a virologist and a spatial omics expert. Together, they embark on a mission to address a pivotal question: Can spatial multiomics be applied to historical samples to unravel the unique aspects of the immune response to the 1918 influenza virus in young adults?