Floods, droughts, heat waves and cold blasts -- why is the weather becoming more extreme? Environmentalist and "America's weatherman" Al Roker discusses the link between climate change and disruptions to weather patterns worldwide, followed by a conversation between Nobel laureate Al Gore and TED science curator David Biello about the science of extreme weather and emerging solutions to reduce the risk of these events. (This segment, introduced by radio researcher Latif Nasser, was part of...

Refrigerators do much more than store your groceries -- they're also vital to preserving and distributing vaccines. Illustrating the realities of (and threats to) global vaccine supply chains, technologist and TED Fellow Nithya Ramanathan describes how smart sensors placed in fridges that store medical supplies can provide crucial, real-time data and ensure people get the life-saving care they need.

What if you could eat chicken nuggets without harming a chicken? It's possible through "cellular agriculture," says Isha Datar. In a talk about cutting-edge science, she explains how this new means of food production makes it possible to eat meat without the negative consequences of industrial farming -- and how it could fundamentally change our food systems for the better. "It's our once-in-a-lifetime opportunity to get a second chance at agriculture," she says.

Your belly and your brain speak to each other, says obesity researcher Mads Tang-Christensen. Offering scientific proof that obesity is a disease influenced by genetics and the environment, he introduces a molecule discovered in both the brain and gut that helps control appetite -- and which could be engineered to promote healthy weight loss for those living with obesity.

Get transported on a stunningly rendered, sci-fi safari through Planet City: an imaginary metropolis of 10 billion people, from the brain of director and architect Liam Young. Explore the potential outcomes of an urban space designed to house the entire population of the earth -- and imagine answers to what is possible, and what is sustainable, for the planet.

Sci-fi writer Chen Qiufan doesn't fear a dystopian future. Instead, he believes developments in artificial intelligence will make all of our lives better, healthier and safer. He takes us on a tour of the next 20 years of AI and shares some astonishing predictions for the advancements in science and technology that could await us. "For every future we wish to create, we must first learn to imagine it," he says.

As COVID-19 spread, BioNTech cofounders Uğur Şahin and Özlem Türeci had one goal: to make a safe, effective vaccine faster than ever before. In this illuminating conversation with head of TED Chris Anderson, the immunologists (and married couple) share the fascinating story of how their decades of mRNA research powered the Pfizer-BioNTech vaccine -- and forecast what this breakthrough science could mean for the future of vaccines and other immunotherapy treatments.

We've misplaced the building blocks of the cosmos -- and particle physicists like Claire Malone are on a mission to find them. Despite scientists hitting a "major snag" in uncovering what exactly makes up dark matter and dark energy, she explains how questioning our fundamental understanding of nature itself invites a different, more meaningful perspective universally.

The universe started with a bang -- but how will it end? With astonishing visuals, cosmologist and TED Fellow Katie Mack takes us to the theoretical end of everything, some trillions of years in the future, in a profound meditation on existence, wonder and the legacy of humanity within the immensity of time and space.

Astrophysicist and TED Fellow Sarah Rugheimer searches for aliens -- but not the cartoony green kind. She's looking for extraterrestrial microbes by studying how these single-celled organisms emit gases, which could reveal evidence of them throughout the cosmos. Wondering if we're really alone in the universe, Rugheimer identifies two big hurdles to confirming life on another world and offers insight into what finding it might mean for us.

The pandemic forced the world to work together like never before and, with unprecedented speed, bore a new age of health and medical innovation. Physician-scientist Daniel Kraft explains how breakthroughs and advancements like AI-infused antiviral discoveries and laboratory-level diagnostic tools accessible via smartphones are paving the way for a more democratized, connected and data-driven future of medicine and personalized care.

Have you ever misplaced something you were just holding? Completely blanked on a famous actor's name? Walked into a room and immediately forgot why? Neuroscientist Lisa Genova digs into two types of memory failures we regularly experience -- and reassures us that forgetting is totally normal. Stay tuned for a conversation with TED science curator David Biello, where Genova describes the difference between common moments of forgetting and possible signs of Alzheimer's, debunks a widespread...

DNA isn't the only builder in the biological world -- there's also a mysterious bioelectric layer directing cells to work together to grow organs, systems and bodies, says biologist Michael Levin. Sharing unforgettable and groundbreaking footage of two-headed worms, he introduces us to xenobots -- the world's first living robots, created in his lab by cracking the electrical code of cells -- and discusses what this discovery may mean for the future of medicine, the environment and even life...

Your teeth carry secrets: centuries of history about your ancestors, from where they lived to what they ate and where they traveled. Bioarchaeologist Carolyn Freiwald traces the story of human migration across the Americas -- from Mayan royalty and Belizean buccaneers to rural Appalachian farmers -- to illustrate what ancient teeth can reveal about you.

What if tiny microparticles could help us solve the world's biggest problems in a matter of minutes? That's the promise -- and magic -- of quantum computers, says Matt Langione. Speaking next to an actual IBM quantum computer, he explains how these machines solve complex challenges like developing vaccines and calculating financial risk in an entirely new way that's exponentially faster than the best supercomputers -- and shares why industries should prepare now for this new leap in computing.

Astronomers once gazed upon the night sky and counted every star in the galaxy by hand. The process has evolved since then, but the thirst for celestial knowledge remains the same. Join astrophysicist Emily Levesque for an anecdote-rich jaunt through the technological history of photographing the cosmos and learn about the one constant that makes it all work: human curiosity.

In April 2020, epidemiologist-in-training Sophie Rose volunteered to be infected with the virus that causes COVID-19. As a young, healthy adult, she's offering to take part in a human challenge trial, a study where participants are intentionally exposed to SARS-CoV-2 to test vaccines and gather critical data. Explaining how challenge trials could speed up the development of effective vaccines, Rose shares why volunteering was the right decision for her.

Take a mind-blowing trip to the lab as TED Senior Fellow Andrew Pelling shares his research on how we could use fruits, vegetables and plants to regenerate damaged human tissues -- and develop a potentially groundbreaking way to repair complex spinal cord injuries with asparagus.

Venom can kill ... or it can cure. In this fascinating talk, marine chemical biologist Mandë Holford shares her research into animal venom, from killer sea snails to platypuses and slow lorises -- and explores its potential to one day treat human diseases like cancer. The mechanism behind this powerful substance is still mysterious, Holford says, but: "Someday, snail venom might just save your life."

Concrete is the second most-used substance on Earth (behind water), and it's responsible for eight percent of the world's carbon footprint. Cement researcher Karen Scrivener shares the research behind a pioneering new kind of cement known as LC3, which could slash carbon emissions from this crucial building material by 40 percent, if adopted at scale.

In the US, Black women are nearly 300 percent more likely to die as a result of childbirth than white women. Sharing appalling statistics on maternal mortality as well as her own tragic story of loss, Wanda Irving explains how racism and bias in health care minimizes and dismisses Black women's pain -- and makes a personal plea for leaders in the medical community to take steps toward reform.

In cities, evolution occurs constantly, as countless plants, animals and insects adapt to human-made habitats in spectacular ways. Evolutionary biologist Menno Schilthuizen calls on peculiar beings such as fast food-loving mice and self-cooling snails to illustrate the ever-transforming wonders of urban wildlife -- and explains how you can observe this phenomenon in real-time, thanks to a global network of enthusiastic citizen scientists.

Far-UVC light is a type of ultraviolet light that kills microbes and viruses and, crucially, seems to be safe to use around humans. Radiation scientist David Brenner describes how we could use this light to stop the spread of SARS-CoV-2, the virus responsible for COVID-19, in hospitals, nursing homes, trains and other public indoor spaces -- paving the way for a potentially game-changing tool in the fight against the coronavirus pandemic. (This virtual conversation, hosted by TED science...

Conventional vaccine testing is a slow, years-long process. As thousands of people continue to die each day from COVID-19, bioethicist Nir Eyal proposes a radical idea that could dramatically accelerate the vaccine development timeline: "human challenge trials," in which scientists would deliberately expose volunteers to the virus to more quickly determine a vaccine's efficacy. (This virtual conversation, hosted by head of TED Chris Anderson, was recorded June 15, 2020.)

At the intersection of precision medicine and vaccinology lies a revolutionary scientific pursuit: personalized vaccines. Infectious disease specialist Ofer Levy introduces this promising medical approach, in which tailored inoculations will enable effective immunization of the most vulnerable among us, including the young and elderly, and shares how we're now venturing into a new era of sustaining and supporting human life. (This talk contains graphic medical imagery.)