This is the second interview with Dr Tom Strawson-Smith, Consultant Clinical Oncologist, at Bristol Haematology and Oncology Centre, UK, concluding the overview of how to manage colorectal cancer.  He discusses how he treats people who have metastatic colorectal cancer, both widely metastatic and those with oligo-metastatic disease, focusing on the use of systemic treatments.  This podcast is an overview of current oncology treatment of metastatic colorectal cancer at registrar level. Your host is Dr Alison Cameron, Consultant Clinical Oncologist, Bristol, UK.