Despite decades of research and relentless messaging about the importance of diet and exercise, type 2 diabetes remains a major threat to the lives of millions of Americans. As new diagnoses in some populations plateau, rates in others groups, including African Americans and Latinos, are increasing. Why does this largely preventable and multifactorial condition persist? What are the latest treatments available for individuals living with diabetes? And what technological and medical breakthroughs lie on the horizon? In this Forum — held on World Diabetes Day — experts in medical innovation, food policy, diabetes and obesity research, and community outreach assessed the promise of new approaches to diabetes, as well as explored remaining challenges. Part of The Dr. Lawrence H. and Roberta Cohn Forums, this event was presented jointly with HuffPost on Tuesday, November 14, 2017.