Climate-related programs face challenges from federal regulation rollbacks and proposed spending cuts. In response, some members of the public and private sectors have stepped in, announcing various commitments to take action to curb climate change. What can cities, states, research institutions and businesses do to lead the way on climate change and to make the greatest impact on the environment and public health? A stellar panel of national, state, corporate and science leaders addressed the question in this Forum. Presented jointly with Reuters on Friday, October 13, 2017.