Irritable bowel syndrome (IBS) impacts more than 45 million Americans and about 1 in 10 globally. So, if you have abdominal pain, diarrhea and/or constipation on a regular basis...you are not alone. We are thrilled to have world-renowned gastroenterologist, Dr. William Chey, on this episode to discuss this diagnosis along with common IBS mimickers.  Dr. Chey is the Chief of Gastroenterology at the University of Michigan and a true physician champion for the importance of a multidisciplinary approach to the management of IBS. He discusses how this complex condition, once perceived purely as a psychosomatic disorder, has evolved into a multifaceted syndrome with new and improved treatment methods. Discover the transformative potential of dietary strategies like the low FODMAP diet, the integration of behavioral therapy along with complementary and alternative medicine (like acupuncture) into patient care, as we explore the nuances of treating IBS and its masqueraders. Dr. Chey sheds light on the enlightening findings from a recent study on disaccharidase deficiencies, particularly the surprising prevalence of sucrase-isomaltase deficiency in IBS patients with diarrhea predominance. Gain insight into the challenges of current testing methods and the role of bile acid malabsorption, which opens the door to a more precise and personalized approach to managing unruly gut symptoms. The conversation steers toward the promise and limitations of breath tests and the significance of a Dream Team approach, blending expertise from various specialists to address the unique needs of each patient.  We also delve into the intricate relationship between small intestinal bacterial overgrowth (SIBO) and bile acid diarrhea, and the innovative work of researchers like Dr. Mark Pimentel. Dr. Chey emphasizes the growing importance of precision medicine in the field of gastroenterology and gut health, highlighting the complexities of diagnosing and treating conditions such as SIBO. While we share a wealth of knowledge that promises to enlighten both healthcare professionals and individuals navigating the intricacies of IBS and it's common mimickers, you won't want to miss the introduction to a very special guest! Welcome Mabel June Scarlata (hint: she's the Scarlata family's new chocolate lab puppy).  Don't forget to subscribe and share – your gut will thank you! P. S. Find Mind Your Gut:  The Science-Based, Whole-Body Guide to Living Well with IBS by Kate Scarlata MPH, RDN and Megan Riehl, PsyD which covers all things IBS along with IBS Mimickers in Chapter 10. Learn more about Kate and Dr. Riehl: Website: www.katescarlata.com and www.drriehl.com Instagram: @katescarlata @drriehl and @theguthealthpodcast Order Kate and Dr. Riehl's book, Mind Your Gut: The Science-Based, Whole-body Guide to Living Well with IBS. The information included in this podcast is not a substitute for professional medical advice, examination, diagnosis or treatment. Always seek the advice of your physician or other qualified health care provider before starting any new treatment or making changes to existing treatment.