This Alexion-sponsored educational podcast is intended for US healthcare professionals only. Neurofibromatosis type 1 (NF1) can create a substantial quality of life burden on patients and their caregivers, and the experience and resilience of each individual patient varies. Of importance is the increased risk for psychosocial and emotional difficulties, such as anxiety, depression, and social withdrawal. This requires special attention at all stages of the condition. Join Drs. Bruce Korf and Karin Walsh as they discuss the psychological impact associated with NF1, the challenges experienced by the multidisciplinary teams and NF clinics involved in treatment and care of the condition, and potential solutions for these challenges. MM/US/DISEASE/1191 October 2023