Even as the New Enclave expands its influence and faces down new threats, the realities of the Wasteland now pose an even greater challenge. The great factories and industrial complex which created and supported the technology which gave the Colonel an edge over the other factions in the region no longer exist. Hard decisions are on the horizon. However, the other residents of Vault 76 have been busy with their own plans. The Morgantown Settlement has become a shiny beacon of hope…that rebuilding is possible, and they are ready to take the next step towards a better future. And in Flatwoods, the New Responders have risen from the ashes of the old. Their mission remains the same - help the people of Appalachia. This work has not gone unnoticed…and the Colonel casts her eye to that small town as well.