“AYAs are underrepresented in clinical trials and unfortunately have one of the highest rates of being uninsured of any population. So, this is really concerning for a lot of reasons and really impacts our ability to make a difference for their treatment and outcomes,” Stacy Whiteside, APRN, MS, CPNP-AC/PC, CPON®, nurse practitioner and fertility patient navigator in the Department of Hematology, Oncology, and Blood and Marrow Transplant at Nationwide Children’s Hospital in Columbus, OH, told Jaime Weimer, MSN, RN, AGCNS-BS, AOCNS®, manager of oncology nursing practice at ONS, during a discussion about increasing AYA enrollment in clinical trials. Whiteside is also the nursing representative for the Children’s Oncology Group (COG) AYA Committee.  You can earn free NCPD contact hours after listening to this episode and completing the evaluation linked below.   Music Credit: “Fireflies and Stardust” by Kevin MacLeod  Licensed under Creative Commons by Attribution 3.0  Earn 0.75 contact hours of nursing continuing professional development (NCPD), which may be applied to the nursing practice, oncology nursing practice, care of the pediatric hematology and oncology patient, or pediatric hematology and oncology nursing practice ILNA categories, by listening to the full recording and completing an evaluation at myoutcomes.ons.org by January 12, 2026. The planners and faculty for this episode have no relevant financial relationships with ineligible companies to disclose. ONS is accredited as a provider of NCPD by the American Nurses Credentialing Center’s Commission on Accreditation.  Learning outcome: The learner will report an increase in knowledge of clinical trial treatment barriers in adolescents and young adults with cancer.  Episode Notes  Complete this evaluation for free NCPD.   Oncology Nursing Podcast:  Episode 9: How to Support Adolescent and Young Adult Patients With Cancer  Episode 19: The Practical Side of Clinical Trials  Episode 126: Oncology Clinical Trials and Drug Development  Episode 260: Diversity in Cancer Clinical Trials  Episode 276: Support Young Families During a Parent’s Cancer Journey  ONS Voice articles:   Balance Hope and Quality of Life for Phase I Clinical Trials  Help Patients Understand Biomarker Test Results and Clinical Trials Options  Nursing Roles in Clinical Trials  Use ClinicalTrials.gov to Find the Right Cancer Research Studies for Your Patients  Clinical Journal of Oncology Nursing articles:   Cancer Clinical Trials: Improving Awareness and Access for Minority and Medically Underserved Communities  Community-Based Clinical Trials: The Role of Nurses in Increasing Enrollment  Disparity of Equitable Representation in Cancer Clinical Trials: Nursing Perspectives  Oncology Nursing Forum article:  Examining Participation Disparities in Cancer Clinical Trials  Perceptions of Clinical Trial Participation Among Women of Varying Health Literacy Levels  Treatment Decision-Making Involvement in Adolescents and Young Adults With Cancer  Clinical Trials ONS Huddle Card  National Cancer Institute’s (NCI’s) National Clinical Trials Network  National Library of Medicine: Clinical Trials  NCI’s Community Oncology Research Program  Children’s Oncology Group (COG)  SWOG Cancer Research Network: Clinical Trials  Journal of Clinical Oncology articles about COG and SWOG:   The Children’s Oncology Group (COG) Adolescent and Young Adult (AYA) Responsible Investigator Network: An Initiative for Advancing AYA Cancer Research in the National Clinical Trials Network  SWOG S1826, a Randomized Study of Nivolumab-AVD Versus Brentuximab Vedotin-AVD in Advanced Stage Classic Hodgkin Lymphoma  To discuss the information in this episode with other oncology nurses, vis